MedDRA Web-Based Browser
Version 3.0 User Guide
27 April 2022
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Acknowledgements
MedDRA Web-based Browser User Guide ii
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Acknowledgements
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Table of Contents
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Table of Contents
1. INTRODUCTION ......................................................................................... 1
2. STARTING THE MedDRA WEB-BASED BROWSER ................................ 2
2.1 Access the WBB and Log In ........................................................... 2
2.2 Components of the WBB Screen .................................................... 3
2.3 WBB Configuration Options ............................................................ 5
3. SEARCHING ............................................................................................... 8
3.1 Search results panel features ....................................................... 11
3.2 Go to browser................................................................................ 11
3.3 Search by code ............................................................................. 12
3.4 Select SOCs to search .................................................................. 12
3.5 Advanced Search .......................................................................... 13
3.6 SMQ search .................................................................................. 14
4. ADDITIONAL SEARCH FEATURES ........................................................ 16
4.1 Export search results .................................................................... 16
4.2 Presentation of results .................................................................. 17
4.3 Search in multiple languages ........................................................ 18
4.4 Synonym list .................................................................................. 20
4.5 Ignore diacritical marks ................................................................. 23
4.6 VCR buttons .................................................................................. 23
4.7 Clear search .................................................................................. 23
4.8 Cancel ........................................................................................... 24
5. USEFUL FEATURES ................................................................................ 25
5.1 History function ............................................................................. 25
5.2 Copy term / Copy code ................................................................. 25
5.3 Open details and occurrences....................................................... 26
5.4 Research bin ................................................................................. 28
5.5 Export research bin to spreadsheet .............................................. 32
5.6 Import a previously exported research bin .................................... 34
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5.7 SMQ Export .................................................................................. 36
5.8 SMQ Analysis................................................................................ 37
5.9 Hierarchy Analysis ........................................................................ 39
6. MedDRA/J SPECIFIC FUNCTIONS .......................................................... 41
6.1 Kana / Kanji ................................................................................... 41
6.2 J-currency ..................................................................................... 43
6.3 MedDRA/J Synonyms – they are displayed under LLTs ............... 45
6.4 MedDRA/J Legend ........................................................................ 48
List of Figures
Figure 2-1. WBB Login Screen ............................................................................ 2
Figure 2-2. WBB End User License Agreement .................................................. 3
Figure 2-3. Components of the WBB Screen ...................................................... 4
Figure 2-4. WBB Configuration Options ............................................................... 5
Figure 2-5. MedDRA Language Availability ......................................................... 6
Figure 3-1. WBB Search Screen .......................................................................... 8
Figure 3-2. WBB Search Results .......................................................................... 9
Figure 3-3. Synonym List.................................................................................... 10
Figure 3-4. Search Options ................................................................................ 11
Figure 3-5. Search Results Panel Features........................................................ 11
Figure 3-6. Go to Browser Results ..................................................................... 12
Figure 3-7. Secondary Link ................................................................................ 12
Figure 3-8. Search by Code ............................................................................... 12
Figure 3-9. Select SOC to Search ...................................................................... 13
Figure 3-10. Select Multiple SOCs to Search ..................................................... 13
Figure 3-11 Search Options ............................................................................... 14
Figure 3-12. SMQ View Option ........................................................................... 14
Figure 3-13. Search SMQs ................................................................................. 15
Figure 3-14. Search SMQ Term Codes .............................................................. 15
Figure 4-1. Export Search Results ..................................................................... 16
Figure 4-2. Search Results Display .................................................................... 17
Figure 4-3. Large Search Results ....................................................................... 17
Figure 4-4. Too Many Results to Display............................................................ 18
Figure 4-5. Search in Three Languages ............................................................. 18
Figure 4-6. Search Results in Three Languages ................................................ 19
Figure 4-7. Search Language Option Menu ....................................................... 20
Figure 4-8 Search Options for Two Languages .................................................. 20
Figure 4-9. View Specific Language Synonym List ............................................ 21
Figure 4-10. German Translation Synonym List ................................................. 22
Figure 4-11. Ignore Diacritical Marks .................................................................. 23
Figure 4-12. VCR Buttons .................................................................................. 23
Figure 4-13. Clear Search .................................................................................. 23
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Figure 5-1. Open History .................................................................................... 25
Figure 5-2. Open History Results ....................................................................... 25
Figure 5-3. Copy Term ....................................................................................... 26
Figure 5-4. Browsers .......................................................................................... 26
Figure 5-5. Open Details & Occurrences ............................................................ 27
Figure 5-6. Term Details in Primary Language ................................................... 28
Figure 5-7. Add to Research Bin ........................................................................ 29
Figure 5-8. Add Multiple Groups to Research Bin .............................................. 29
Figure 5-9. Remove Terms From Research Bin ................................................. 30
Figure 5-10. Add Selected Levels to Research Bin ............................................ 31
Figure 5-11. Excluding levels from the Research Bin ......................................... 31
Figure 5-12. My Research Bin ............................................................................ 32
Figure 5-13. Research Bin Label ........................................................................ 33
Figure 5-14. Export Spreadsheet ....................................................................... 34
Figure 5-15. Import Previously Exported Spreadsheet ....................................... 34
Figure 5-16. Imported Terms Results ................................................................. 35
Figure 5-17. SMQ Export.................................................................................... 36
Figure 5-18. Include Inactive Terms ................................................................... 36
Figure 5-19. Export SMQ Contents .................................................................... 37
Figure 5-20. SMQ Contents Spreadsheet .......................................................... 37
Figure 5-21. SMQ Analysis Search Options ....................................................... 38
Figure 5-22. Inputs for Analysis .......................................................................... 38
Figure 5-23. SMQ Analysis Report ..................................................................... 38
Figure 5-24. Hierarchy Analysis Inputs ............................................................... 39
Figure 5-25. Input for Analysis ............................................................................ 39
Figure 5-26. Hierarchy Analysis Report .............................................................. 40
Figure 6-1. Select Language Option ................................................................... 41
Figure 6-2. Kana Translation Option .................................................................. 41
Figure 6-3. Kana / Kanji Translation ................................................................... 42
Figure 6-4. Open Kana Details & Occurrences .................................................. 42
Figure 6-5. Kana Term Details ........................................................................... 43
Figure 6-6. J-currency Status ............................................................................. 43
Figure 6-7. Open Details & Occurrences_J-currency ......................................... 44
Figure 6-8. Open History _J-currency ................................................................ 45
Figure 6-9. J-currency History Results ............................................................... 45
Figure 6-10. Search for a Term .......................................................................... 46
Figure 6-11. Japanese Term – Go to Browser ................................................... 47
Figure 6-12. Go to Browser Results ................................................................... 47
Figure 6-13. Results_ J-synonyms ..................................................................... 48
Figure 6-14. J-currency and Japanese Synonym List Identifiers ........................ 49
Introduction
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1. INTRODUCTION
Welcome to the MedDRA® Web-Based Browser (WBB) User Guide. This guide has
been developed to familiarize the reader with the use of the MedDRA Web-Based
Browser.
The WBB is designed to review the MedDRA hierarchy and SMQs, and perform
term searches for coding and analysis tasks in English and available translated
languages.
This guide assumes the viewer has a basic understand of how MedDRA is used for
regulatory reporting and analysis and knowledge of MedDRA’s hierarchical
structure.
For more information about the MedDRA Web-Based Browser, questions, or
comments about this guide, please contact the MedDRA MSSO at:
Email: mssohelp@meddra.org
Starting the MedDRA Web-Based Browser
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2. STARTING THE MedDRA WEB-BASED BROWSER
This section describes basic WBB functions and contains the following:
Access the WBB and Log in
Components of the WBB screen
Web Configuration Options
2.1 Access the WBB and Log In
The MedDRA WBB is a free tool that is part of your MedDRA subscription.
To log into the WBB, go to the following link: https://tools.meddra.org/WBB. You will
be presented with the Login screen.
Figure 2-1. WBB Login Screen
Click on the MedDRA End User License Agreement link to read the Terms of Use
governing your use of the WBB.
To log in, select a preferred language for the user interface, and then use your
MedDRA ID and password. This is the same MedDRA ID and password used to
access portions of the MedDRA website and other web-based tools such as MVAT.
Note: When logging on for the first time, the End User License Agreement
appears.
Starting the MedDRA Web-Based Browser
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Figure 2-2. WBB End User License Agreement
Please review the information in the End User License Agreement and click on
I Agree to continue to the WBB home screen.
Subsequent logins will take you immediately to the WBB home screen.
2.2 Components of the WBB Screen
The WBB interface is laid out in five panels.
Starting the MedDRA Web-Based Browser
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Figure 2-3. Components of the WBB Screen
A. At the top are WBB configuration options and useful information. These include the
ability to change languages, MedDRA version, and switch between SOC and SMQ
view.
B. To the left is the MedDRA hierarchy panel where one can browse the hierarchy by
left clicking the plus symbol next each term to drill down to the LLT level.
Just above the MedDRA hierarchy panel is the Term Navigation panel. The
hierarchy information reduces the need to scroll up to recall which SOC, HLGT you
are browsing in.
C. In the middle is the search panel where words or MedDRA codes may be entered to
search for MedDRA terms.
Starting the MedDRA Web-Based Browser
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D. The bottom / middle is where the search results are displayed
E. To the right is term detail information. When clicking on a MedDRA term in the
hierarchy panel (B) or in search results (D), the term details display in this far right
panel.
2.3 WBB Configuration Options
The WBB configuration and information options are shown below.
Figure 2-4. WBB Configuration Options
MedDRA Concept Descriptions
– Concept descriptions as found in Appendix B of the MedDRA Introductory Guide
Legends
– an explanation of the color codes used to convey hierarchical link information or
term status in both the SOC view and the SMQ view
Search history
– retrieve the history of a given term
New browser window
– opens a new browser window for comparing two different versions of MedDRA
MedDRA Documentation
– links to MedDRA Release support documentation found on the MedDRA website
User Guide
- links to this document
Starting the MedDRA Web-Based Browser
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SMQ Analysis
– opens a new browser window for performing an SMQ analysis on a set of imported
MedDRA terms including secondary SOC path
Hierarchy Analysis
– opens a new browser window for performing a hierarchy analysis on a set of
imported MedDRA terms including secondary SOC path
Language options
– provides views of up to three supported languages simultaneously
Browser View SOC vs. SMQ
– default will show the SOC view of MedDRA; SMQ view displays the SMQ
information in the hierarchy panel of the left
Version section
– select desired version of MedDRA
Note that not all languages are available in earlier versions of MedDRA. See below:
Figure 2-5. MedDRA Language Availability
Starting the MedDRA Web-Based Browser
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Show codes
– displays the MedDRA code next to each term. By default, the WBB will show non-
current LLTs, which are depicted with a red square and lettering.
Release and Supplemental English
– allows user to toggle between the official release versions and the latest updates of
the supplemental data, in English only, that will become part of the next release.
Restore Defaults
– allows user to revert back to their default browser application settings such as
languages, between SOC and SMQ Views, toggling between displaying codes, and release
versions.
Searching
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3. SEARCHING
This section describes how to perform searches in the WBB and explains what the
search functions in the search panel produce.
Figure 3-1. WBB Search Screen
To search, enter a term or word in the Search screen (C).
The search function performs a logical and operation and return terms with those
words found in any order.
When results are returned, a summary of the search results appears (D) showing
the total number of terms returned and a hierarchical breakdown of results – for
example how many LLTs, PTs, HLTs, etc.
Similarly, the results are divided in separate tabs according to their place in the
MedDRA hierarchy – LLT, PT, HLT, etc.
LLTs will show first if there are any in a search result.
By default, a search will break up returned results into four search categories at the
PT and LLT level.
Searching
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Figure 3-2. WBB Search Results
Exact match – result matches exactly what was typed into the search field
Lexical variant – returns different word order of words typed into the search
field. In this case the search returned the lexical variant “failure liver” from the
search of “liver failure.”
Synonym search results – return results based on the associated synonym
list file. Notice the search for liver failure returned terms that contain hepatic in
them.
o Synonyms are returned based on predefined synonym groups that may be
viewed by clicking the “Use Synonym List” link found in the search panel
(C).
Searching
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Figure 3-3. Synonym List
o These pairings have been tested to ensure they bring up appropriate
associations. For example, “liver” terms return “hepatic”; “kidney terms”
return “renal terms”; and vice versa.
o The synonym search function may be disabled by unchecking the check
box to the left of “Use Synonym List.”
Searching
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Figure 3-4. Search Options
Contains search results – terms that contain word or words entered in the
search field.
If you prefer to not group research results according to the search categories, this
function may be disabled by unchecking “Show PT/LLT with categories” option
which will return results in alphabetical order.
3.1 Search results panel features
To view the hierarchy of higher level terms and multi-axial links, expand the search
results. The primary SOC is designated with a blue square.
Figure 3-5. Search Results Panel Features
3.2 Go to browser
To use this feature, right click on a term in the search results panel (PT Cardiac
death) and choose “go to browser.” A second browser window pops up displaying
the hierarchy information and takes the user to the place within MedDRA where that
term is located and the surrounding terms.
Searching
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Figure 3-6. Go to Browser Results
In this case there are two links – a primary link to SOC General disorders and
administration site conditions which is designated by the blue box surrounding the
“SOC” icon, and a secondary link to SOC Cardiac disorders.
To see the secondary link in the MedDRA hierarchy, click on the LLT in the
secondary link on the left side of the screen to see the surrounding LLTs and PTs
are.
Figure 3-7. Secondary Link
3.3 Search by code
In addition to words, one may also enter a MedDRA code in the search field to
search by code.
Figure 3-8. Search by Code
3.4 Select SOCs to search
To limit which SOCs to search from, select one or more SOC(s) from the “Select
SOCs to search” window. For example, if you were interested in investigation terms
and did not want terms from other SOCs, select the Investigation SOC to limit
searches to this single SOC.
Searching
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Figure 3-9. Select SOC to Search
Multiple groups of SOCs can be selected by holding down the shift key and clicking
on SOC names.
Notice that when a search is limited to a subset of the 27 SOCs, there is a yellow
highlighted message informing the user that search is limited to the number of SOCs
selected.
Figure 3-10. Select Multiple SOCs to Search
To search all 27 SOCs again, click the “Clear Selection” button.
3.5 Advanced Search
This function allows for more complex and filtered searches for terms.
Searching
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Figure 3-11 Search Options
The first operator is a string operator and the options are CONTAINS, BEGINS WITH,
ENDS WITH, and EXACT MATCH. The second operator is for Boolean operators such as
AND, OR. The third operator is a string operator again and the options are CONTAINS,
BEGINS WITH, ENDS WITH, EXACT MATCH, and NOT CONTAINS.
Synonyms are only included for the search term associated with the CONTAINS operator.
Searching for MedDRA codes does not work in this function.
3.6 SMQ search
Performing searches for SMQs is similar to performing searches in the SOC view.
First switch the browser view to SMQ view.
Figure 3-12. SMQ View Option
Enter a word or words to search in the search field.
Searching
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Figure 3-13. Search SMQs
As demonstrated in the SOC view, one can search for MedDRA term codes and -
specific to the SMQ view – SMQ codes may be entered for searching.
Enter the SMQ code in the Search Options screen and press Search.
Figure 3-14. Search SMQ Term Codes
Additional Search Features
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4. ADDITIONAL SEARCH FEATURES
In addition to the above search functions, there are additional search features
available in the WBB.
4.1 Export search results
To export search results to a spreadsheet, after performing a search, click on
“Export” in the Search Options screen.
Figure 4-1. Export Search Results
A popup window appears displaying the search results. Note that MS Excel or compatible
spreadsheet software must be installed on your computer for this feature to work.
Additional Search Features
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Figure 4-2. Search Results Display
Secondary SOC hierarchy information is included by default when exporting search
results. This option may be unchecked if only primary SOC information is needed.
Similarly, HLGT and HLT terms are included in exports by default. If these terms are
not needed, they can be excluded from the export by unchecking these levels in
export options.
Click “Export” to export your results to a spreadsheet. The exported spreadsheet will
contain a separate worksheet for each level of the hierarchy identified in the search.
4.2 Presentation of results
Different web browsers, such as Internet Explorer® and Chrome™ browser for
example, have different approaches in how the load information from a server to
present to the user. To account for these differences, the Web-Based Browser has
been designed to optimize the user experience based on the number of results
returned.
Search results will be expanded for all search categories displaying all terms found if
the number of results is small (20 or less). Exceptions:
For searches resulting in dozens of terms, the “synonym search results” and the
“Contains Search” in the PT and LLT tab will show collapsed, but may be expanded
to see the results.
Figure 4-3. Large Search Results
Additional Search Features
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For searches resulting in thousands of terms, a message will appear stating “Your
search has returned too many results to display. Click the Export button to export
your results to a spreadsheet.”
Figure 4-4. Too Many Results to Display
4.3 Search in multiple languages
The WBB has the capability of searching in three supported languages. From the
Configuration options fields, choose three languages. In the example below, three
languages have been selected in the following order: German, English and Spanish.
Figure 4-5. Search in Three Languages
One can see what language the browser is set to search by looking to the left of the
search field. Type in a German word to search (sodbrennen). The search returns
items with the German, English, and Spanish words.
Additional Search Features
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Figure 4-6. Search Results in Three Languages
The language to search can be changed by using the drop down menu to the left of
the search field. Only the languages selected in the language options menu will
appear. In the example below, the search language was changed to English.
Additional Search Features
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Figure 4-7. Search Language Option Menu
To search or view two languages only, simply make two of the three language
choices the same.
Figure 4-8 Search Options for Two Languages
4.4 Synonym list
There is an associated synonym list for each of the supported languages. To view
this list, click on the “Use Synonym List” link in the search panel.
To view a list to a specific language, that language must be the primary language
selected.
Additional Search Features
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Figure 4-9. View Specific Language Synonym List
A popup screen appears with the synonym list for the selected language.
Additional Search Features
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Figure 4-10. German Translation Synonym List
The synonym search function can be disabled by unchecking the “Use Synonym
List” feature.
Additional Search Features
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4.5 Ignore diacritical marks
By default, the “ignore diacritical marks” option is enabled for searching. This means
that diacritical marks such as accents, tildes, and umlauts used in non-English Latin
alphabet languages are ignored when performing a search. This alleviates the user
from having to remember the correct diacritical marks for words.
“Ignore diacritical marks” can be disabled by unchecking this option:
Figure 4-11. Ignore Diacritical Marks
4.6 VCR buttons
The arrow icons below the search button provide a way to go back or forward
through searches performed within a WBB session.
Figure 4-12. VCR Buttons
For example, clicking on the left < arrow goes back to the previous word or words
searched. The right > arrow moves one search forward within the set of terms
selected.
The outside arrows go to the very first term searched within a WBB session or to the
last term searched within a WBB session.
4.7 Clear search
To clear the search results panel and the search field, press the “Clear Search”
button.
Figure 4-13. Clear Search
Additional Search Features
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4.8 Cancel
To stop a search in progress, press the “Cancel” button.
Useful Features
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5. USEFUL FEATURES
5.1 History function
To view basic historical information about a MedDRA term, right click on the term in
either the search results panel or the hierarchy panel and select “Open History.”
Figure 5-1. Open History
A history window will appear showing basic history information for the selected term:
Figure 5-2. Open History Results
5.2 Copy term / Copy code
To copy a term name or MedDRA code into the computer’s clipboard for pasting in a
document, right click a term in either the search results panel or the hierarchy panel
Useful Features
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and select either “Copy Term” to copy the term name, or “Copy Code” to copy the
MedDRA code.
Figure 5-3. Copy Term
This function behaves differently depending on the web browser being used. Internet
Explorer users may receive a warning message the first time the function is used.
For Firefox, Chrome, and other browsers, a prompt appears asking the user to press
the CTRL + C keys to copy the term or code.
Internet Explorer Firefox / Chrome / Safari / Microsoft Edge
Figure 5-4. Browsers
The term name or term code can be pasted into another document such as a word
document.
5.3 Open details and occurrences
To view open details and occurrences of a term, right click on the term in either the
search results panel or the hierarchy panel and select “Open Details and
Occurrences.”
Useful Features
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Figure 5-5. Open Details & Occurrences
A details and occurrences window will appear showing similar information as shown
in the term details panel on the lower right of the WBB.
Additionally, term occurrences in MedDRA hierarchy and placement in SMQs are
displayed.
Useful Features
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Figure 5-6. Term Details in Primary Language
5.4 Research bin
The research bin collects and stores terms during a WBB session for research
purposes.
To add a term to the research bin, right click on a term and press “Add to Research
Bin.”
Useful Features
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Figure 5-7. Add to Research Bin
Multiple groups of sequential terms can be added to the research bin by selecting
and holding down the shift key and clicking on term names.
Figure 5-8. Add Multiple Groups to Research Bin
Multiple non-sequential terms can be added to the research bin by holding down the
control key and clicking individual terms.
Useful Features
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Individual terms in the research bin may be removed by clicking the check box next
to the term and selecting “Remove” at the top of the research bin:
Figure 5-9. Remove Terms From Research Bin
The entire research bin contents may be removed by clicking “Clear All.”
A term and all subordinate terms may be added at one time by right clicking on a
term and selecting “Add Selected Levels to Research Bin.”
Useful Features
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Figure 5-10. Add Selected Levels to Research Bin
The user will be prompted to uncheck any levels they do not want to include when
adding terms to the research bin via the “Add selected Levels to Research Bin”
option.
Figure 5-11. Excluding levels from the Research Bin
After unchecking any levels to exclude and clicking “next”, the research bin is
displayed.
Useful Features
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Figure 5-12. My Research Bin
5.5 Export research bin to spreadsheet
Before exporting the research bin to a spreadsheet, there is an option to label the
research bin. Enter a topic name in the “Research Topic” field above and click on
“Export.”
Useful Features
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Figure 5-13. Research Bin Label
Secondary SOC hierarchy information is included by default when exporting from the
research bin. This option may be unchecked if only primary SOC information is
needed. Similarly, the HLGT and HLT hierarchy is included in exports by default. If
these terms are not needed, they can be excluded from the export by unchecking
these levels in export options.
Included in the export spreadsheet are the topic name, if entered, a date/time stamp,
and the term codes and names, levels, the accompanying primary SOC hierarchy,
and the secondary SOC path, if selected.
Useful Features
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Figure 5-14. Export Spreadsheet
It is important to understand that the WBB does not store research bin contents after
logging off or your session has timed out due to inactivity. To overcome this
limitation, users may export a research bin to a spreadsheet and import it at a later
time. This function permits the user to save their work and begin again later.
5.6 Import a previously exported research bin
To import a previously exported research bin, from the “My Research Bin” screen,
press the “Browse” button to find the spreadsheet on your local computer or local
network.
Click “Import.”
Figure 5-15. Import Previously Exported Spreadsheet
Useful Features
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Results:
Figure 5-16. Imported Terms Results
Useful Features
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5.7 SMQ Export
To export an SMQ and its related PTs to a spreadsheet, select SMQ view. Right
click on an SMQ and select “SMQ Export.”
Figure 5-17. SMQ Export
You will be presented with a popup window. By default, inactive PTs are not
included in an export, but this can be overridden by selecting the “Include Inactive
terms” checkbox.
Figure 5-18. Include Inactive Terms
Press “Export” to export the contents of an SMQ to a spreadsheet. You will be
presented with the following popup screen. Press Open.
Useful Features
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Figure 5-19. Export SMQ Contents
Notice that the contents of the SMQ, including the SMQ name, PTs, and PT scope
are included. The yellow highlighted rows are inactive PTs. Remember inactive PTs
would only be included in an export if the “include inactive PTs” check box was
checked.
Figure 5-20. SMQ Contents Spreadsheet
5.8 SMQ Analysis
This function allows user to determine which SMQs are associated with a set of
uploaded MedDRA terms. To perform this analysis, you will first need to select
language/MedDRA version, and search type (narrow, broad, and algorithmic).
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Figure 5-21. SMQ Analysis Search Options
Then, import a spreadsheet with the desired MedDRA terms. Data must be in a
Microsoft Office Excel or compatible spreadsheet with the first row containing the
column headers and with data starting on the second row. Four columns are
required in the following order (Row ID, LLT/PT Term, LLT/PT Code, Case ID). The
Row ID value is optional (note the row ID column is required). Either the LLT/PT
Term or LLT/PT Code must be provided. The Case ID is optional unless you’re
planning on doing an Algorithmic Search, in which case, Case ID is required.
Figure 5-22. Inputs for Analysis
After generating the report, you can export it to a spreadsheet.
Figure 5-23. SMQ Analysis Report
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5.9 Hierarchy Analysis
This function lets you retrieve the MedDRA hierarchy of multiple terms uploaded at
one time and optionally includes the secondary SOC path. To perform this analysis,
you must first select the language and MedDRA version. Also, select any preferred
options for what data you want to export to a spreadsheet.
Figure 5-24. Hierarchy Analysis Inputs
Next, import the spreadsheet with the desired MedDRA terms. Data must be in a
Microsoft Office Excel or compatible spreadsheet with the first row containing the
column headers and with data starting on the second row. Three columns are required
in the following order (Row ID, Term, Code). The Row ID value is optional (note the
row ID column is required). Either the Term or Code must be provided.
Figure 5-25. Input for Analysis
After generating the report, you can export it to a spreadsheet for further analysis.
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Figure 5-26. Hierarchy Analysis Report
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6. MedDRA/J SPECIFIC FUNCTIONS
While the concept and contents of the Japanese version of MedDRA are exactly the
same for English as they are in all of the other supported languages, there are some
unique features in the Japanese translation of MedDRA due to language, culture,
and medical practice.
To use the Japanese MedDRA features in the WBB, Japanese must be set to the
primary language. Select “SOC View.”
Figure 6-1. Select Language Option
6.1 Kana / Kanji
The Japanese version of MedDRA contains a translation for both Kanji and Kana.
Kanji is the written form of Japanese displayed in the hierarchy view and term detail
information. The Kana translation is used to help the reader of Japanese know how
to pronounce the Kanji term, and is provided for current LLTs and higher level terms
– PT, HLT, etc.
To see the Kana translation of the Kanji terms in the hierarchy panel, click the
“Kana” checkbox in the configuration options panel.
Figure 6-2. Kana Translation Option
Notice that the Kana translation appears to the right of the Kanji translation
separated by a slash.
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Figure 6-3. Kana / Kanji Translation
Additionally, the Kana translation is always displayed in the term details information
found in the term details panel and the “Open details and Occurrences” right click
option.
Figure 6-4. Open Kana Details & Occurrences
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Figure 6-5. Kana Term Details
6.2 J-currency
In the Japanese translation of MedDRA, there is an additional currency flag for LLTs
to address instances when two or more English LLTs are translated to the same
Japanese term. Japanese MedDRA currency – called J-currency – ensures the
uniqueness of Japanese MedDRA terms by flagging only one of the duplicated
translations for current use.
The WBB supports several methods to identify the J-currency status of LLTs.
When browsing the MedDRA hierarchy at the LLT level, a blue Japanese text to the
right of an LLT separated by parentheses indicates a term that has been set to J non-
current status.
Figure 6-6. J-currency Status
Click on the LLT and refer to the Term detail panel.
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Note the J-currency flag is set to “No.” The same information appears in the Open
Details and Occurrences popup.
Right click on the term and select “Open Details and Occurrences.”
Figure 6-7. Open Details & Occurrences_J-currency
To view changes to the J-currency status, right click on the term and select “Open
History.”
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Figure 6-8. Open History _J-currency
Figure 6-9. J-currency History Results
Notice both LLT currency and the J-currency information are indicated.
6.3 MedDRA/J Synonyms – they are displayed under LLTs
To address some of the linguistic challenges described earlier, the Japanese
Maintenance Organization distributes a Japanese synonym file with each MedDRA
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Japanese translation release. This synonym file is built into the WBB and is different
than the synonym search function explained in the WBB search section, which
applies to English and the other supported languages. The Japanese synonyms are
linked to the LLTs and will appear below the LLTs in the MedDRA hierarchy.
To view the Japanese synonym for an LLT, search for a term.
Figure 6-10. Search for a Term
Right click on the term and select “Go to Browser.”
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Figure 6-11. Japanese Term – Go to Browser
Figure 6-12. Go to Browser Results
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The synonyms appear below the LLT level in the hierarchy view:
Figure 6-13. Results_ J-synonyms
6.4 MedDRA/J Legend
In addition to the other color code explanations, the J-currency and Japanese
synonym list identifiers are presented in the legend to help users remember what
these symbols mean. They appear in both SOC and SMQ legends.
Note that the symbols specific to Japanese MedDRA will only show in the legend if
Japanese is selected as one of the three language options.
To view the J-currency and Japanese synonym list identifiers, click on Legends.
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Figure 6-14. J-currency and Japanese Synonym List Identifiers
––––––––––––––––––––––––––––––––––
For more information about the MedDRA Web-Based Browser, questions,
or comments about this guide, please contact the MedDRA MSSO at:
mssohelp@meddra.org.
